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KMID : 0358420080510091030
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Korean Journal of Obstetrics and Gynecology
2008 Volume.51 No. 9 p.1030 ~ p.1033
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Gestational trophoblastic disease in a patient with twin pregnancy consisting of complete hydatidiform mole and co-existing live fetus after in vitro fertilization
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Kim A-Ri
Ahn Hyun-Young
Shin Jong-Chul
Bae Seog-Nyen
Han Ji-Eun
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Abstract
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A 45-year-old, multigravida woman who had been pregnant with dichorionic twins after in vitro fertilization (IVF) was referred due to early onset of severe preeclampsia. Ultrasonographic findings were multicystic tumor and normal placenta with a live fetus appropriate for 14 weeks of gestation. After therapeutic abortion, the multicystic tumor showed hydropic feature. The fetus had no anomalous finding. Histopathologic analysis revealed complete hydatidiform mole and normal placental tissue attaching three vesseled umbilical cord. Gestational trophoblastic disease (GTD) was diagnosed due to rising levels of serial β-hCG values and abnormal sonographic findings.The patient treated with combined chemotherapy. We report a case of a complete hydatidiform mole and coexisting normal live fetus after IVF, which was complicated with early onset severe preeclampsia and persistent GTD.
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KEYWORD
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Gestational trophoblastic neoplasms, Twins, Hydatidiform mole, Fertilization in vitro
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